Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 4:41 AM
Ignite Modification Date:
2025-12-25 @ 4:41 AM
NCT ID:
NCT07303218
Eligibility Criteria:
Inclusion Criteria:
1. Participant is willing and able to give informed consent for participation in the study. However, since a part of the study is retrospective and, considering the large sample sizes required and considering that the disease involved in this study affects elderly subjects with co-morbidities and presents a significant mortality rate based on the stage of the disease, deceased and untraceable patients will also be included.
2. Age ≥18 years old
3. Have a metastatic histologically confirmed NSCLC
4. Presence of EGFR common mutations (i.e. ex19del and L858R)
5. Have sufficient biological material to assess genomic profiling with AmoyDx Focus panel or similar
6. Clinical data available
Exclusion Criteria:
1. Insufficient baseline tumour tissue (unsuitable for HRD scoring)
2. Presence of EGFR uncommon mutations (i.e. ex20ins)
3. Known presence of co-occurring uncommon EGFRm, ALK, ROS1, or other main oncogenic drivers.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT07303218
Study Brief:
Protocol Section:
NCT07303218