Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 4:32 AM
Ignite Modification Date:
2025-12-25 @ 4:32 AM
NCT ID:
NCT06983418
Eligibility Criteria:
Inclusion Criteria:
* Age ≥ 18 years
* Diagnosis of Obesity Hypoventilation Syndrome (OHS), either pre-existing or newly established during ICU admission
* Admitted to the intensive care unit (ICU) with acute hypercapnic respiratory failure, defined as:
* Arterial pH \< 7.35
* PaCO₂ \> 45 mmHg
* Thyroid function tests performed within 24 hours of ICU admission
* Written informed consent provided by patient
Exclusion Criteria:
* Known history of thyroid disease (e.g., hypothyroidism, hyperthyroidism, thyroiditis, central hypothyroidism)
* Presence of acute conditions known to affect thyroid function tests, including:
* Sepsis
* Pneumonia
* Active malignancy
* Liver cirrhosis
* Kidney failure
* Heart failure
* Use of medications affecting thyroid function, including:
* Corticosteroids
* Amiodarone
* Iodinated contrast agents
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT06983418
Study Brief:
Protocol Section:
NCT06983418