Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 4:31 AM
Ignite Modification Date:
2025-12-25 @ 4:31 AM
NCT ID:
NCT04734418
Eligibility Criteria:
Inclusion Criteria:
* Sign the informed consent form voluntarily and follow the plan requirements;
* Age from 18 to 75 years old (including 18 and 75 years old), regardless of gender;
* Patients who received non-invasive mechanical ventilation after cardiac surgery and were intolerant of non-invasive ventilation.
Exclusion Criteria:
* A history of allergy to any component of the study drug;
* Visual analogue scale of pain (VAS) score \>4；
* Who had taken dexmedetomidine within 8 hours prior to the study;
* Who had used remifentanil within 2 hours before the study began;
* Expectoration difficulties;
* Women who are pregnant or lactating;
* Coma or uncontrollable convulsions;
* Have a history of mental illness or cognitive impairment;
* Delirium before the study began;
* Patients with severe liver dysfunction (CTP grade C);
* Patients with renal insufficiency (patients receiving renal replacement therapy);
* Preoperative left ventricular ejection fraction (LVEF) \< 30%;
* History of drug and alcohol abuse;
* Other conditions that the investigator deems inappropriate for participation in this clinical trial.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
75 Years
Study:
NCT04734418
Study Brief:
Protocol Section:
NCT04734418