Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 4:30 AM
Ignite Modification Date:
2025-12-25 @ 4:30 AM
NCT ID:
NCT03919318
Eligibility Criteria:
Inclusion Criteria:
* Participants between 18 - 60 years of age,
* Good oral hygiene,
* Have not taken any analgesics in the last day,
* Have not taken antibiotics in the last week,
* Patients diagnosed with asymptomatic irreversible pulpitis caused by deep carious lesion on the mandibular first or second molar teeth.
* A prolonged positive response to cold vitality tests,
* The presence of pulp, which is exposed during caries removing and bleeding with a dense and thick consistency.
* The periapical region was healthy in radiographic diagnosis.
Exclusion Criteria:
* Devital teeth that have no response to pulp test,
* The presence of advanced periodontal disease,
* Having a systemic disease that requires antibiotic prophylaxis,
* Radiographically more than 30° root inclination, presence of clear apex, presence of calcification, presence of root resorption,
* The need for root canal treatment which is mesial and/or distal neighbour of the tooth to be treated,
* The presence of a sinus tract in the relevant tooth region,
* Having systemic diseases that reduce immune system resistance,
* Participants with allergic sensitivity to materials and agents that should be used during the root canal treatment,
* Allergic sensitivity to local anesthetics,
* Pregnant participants or participants in the lactation period,
* Over preparation or over filling during treatment,
* Teeth which cannot be applied a rubber-dam,
* Teeth which was damaged enough to require coronal fiber post application,
* Sensitive to Ibuprofen based analgesics.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
60 Years
Study:
NCT03919318
Study Brief:
Protocol Section:
NCT03919318