Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 2:49 PM
Ignite Modification Date:
2025-12-24 @ 2:49 PM
NCT ID:
NCT03721159
Eligibility Criteria:
Inclusion Criteria:
1. Patients willing to participate in the study.
2. Patients within the age group of 35-65 years.
3. Should have ≥ 10 natural teeth.
4. For group I Generalized chronic periodontitis patients with coronary heart disease: Generalised chronic periodontitis is defined as those having 30% or more sites with clinical attachment loss (CAL) ≥ 3mm.
5. For group II Generalized chronic periodontitis patients without coronary heart disease.
6. Healthy controls were selected based on the following criteria: Probing pocket depth (PD) less than 4mm, bleeding on probing (BOP) at ≤15% of tooth sides, and no periodontal treatment (Scaling and root planning or periodontal surgery) within the previous six months.
Exclusion Criteria:
1. Patients with systemic conditions such as type I, type II and pre diabetes mellitus, respiratory diseases, renal disease, liver disease, collagenosis, rheumatoid arthritis, allergy, advanced malignancies and HIV infection were excluded from the present investigation.
2. Use of drugs such as corticosteroids, antibiotics within 6 month of investigation and immuno-suppressive chemotherapy.
3. Smokers and other behavioural factors which may influence the study.
4. Patients who had undergone periodontal therapy within the previous 6 months.
5. Female patients (due to hormonal changes and pregnancy which may alter the oral flora).
Healthy Volunteers:
True
Sex:
MALE
Minimum Age:
35 Years
Maximum Age:
65 Years
Study:
NCT03721159
Study Brief:
Protocol Section:
NCT03721159