Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 4:26 AM
Ignite Modification Date:
2025-12-25 @ 4:26 AM
NCT ID:
NCT01048320
Eligibility Criteria:
Inclusion Criteria:
* age \> 18 years
* gemcitabine-refractory, histologically confirmed pancreatic cancer (progression during or within 6 months of first-line treatment)
* locally advanced or metastatic disease with measurable or non-measurable disease
* life expectancy of greater than 10 weeks
* prior treatment with investigational therapies including EGFR and VEGF antagonists is allowed when administered\>4 weeks prior to start of therapy
Exclusion Criteria:
* any serious uncontrolled medical condition
* prior radiation treatment is not allowed
* no prior chemotherapy within the previous 4 weeks
* known peripheral neuropathy \> CTCAE v 3.0 grade 1; absence of the deep tendon reflexes as the sole neurological abnormality does not render the patient ineligible
* known brain metastases
* lack of physical integrity of the upper GI tract, malabsorption syndrome, or inability to take oral medication
* fertile women (\<2 years after last menstruation) and men of childbearing potential not willing to use effective contraception
* pregnancy or breast feeding
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT01048320
Study Brief:
Protocol Section:
NCT01048320