Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 4:23 AM
Ignite Modification Date:
2025-12-25 @ 4:23 AM
NCT ID:
NCT05188820
Eligibility Criteria:
Inclusion Criteria:
* \- 40 years old or more; given the low prevalence of facet pain in younger adults
* LBP present for more than six months, with an axial predominance
* Persistent LBP after three months of non-interventional treatment
* Pretreatment ODI score of at least 30/100 (moderate disability associated with LBP)
* Pretreatment LBP VAS of at least 4/10
* 80% LBP reduction 30 minutes after 2 intra-articular diagnostic blocs with Xylocaine and Marcaine
* Radiological signs of facet joint degeneration (on X-rays, CT Scan or MRI)
* Absence of neurological deficit
* Sufficient knowledge of French or English to complete the questionnaires
Exclusion Criteria:
* \- Less than 40 years old
* Failure to achieve intra-articular diagnostic block
* Intra-articular injection of CS 3 months or less before recruitment
* Oral corticosteroid use in the last two weeks
* Inflammatory disease
* Systemic infection
* Infection at injection site
* Vertebral fracture
* Spine tumour
* Surgical intervention at injection site prior to the study or planned
* Cognitive disorder that impairs the ability to answer the questionnaires
* Pregnancy
* Breastfeeding
* Coagulopathy affecting platelets
* Drug affecting platelets that cannot be stopped (except acetylsalicylic acid)
* Intolerance or allergies to local anesthetics, contrast agent, CS, and blood products
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
40 Years
Study:
NCT05188820
Study Brief:
Protocol Section:
NCT05188820