Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 4:19 AM
Ignite Modification Date:
2025-12-25 @ 4:19 AM
NCT ID:
NCT03249220
Eligibility Criteria:
Inclusion Criteria:
* Adult male or female patient, aged 18 - 75 years
* Brain injured patients with acute intracranial hemorrhage (including aneurysmal subarachnoid hemorrhage (SAH) and spontaneous intracerebral hemorrhage (ICH)) who are admitted to the ICU and have an indication for ICP monitoring and CSF drainage, as per standard patient care
* Informed consent obtained for research in emergency situations according to HRA art. 30 \& 31 at time of inclusion
Exclusion Criteria:
* Known kidney disease, defined as plasma creatinine \> 120 μmol/l
* Known liver disease, defined as AST \> 200 IU/L
* Over-active thyroid or benign tumors of the thyroid
* History of allergic disorders, including allergic reactions, against contrast agents containing iodine, or against ICG
* Patients which have received one of the following medications before being admitted to ICU: Haloperidol, Meperidine, Methadone, Morphine, Phenobarbital and Rifamycin.
* Patients with wounds or scars including the front orbital region.
* Cerebrospinal fluid infection or signs of meningo-encephalitis
* Anemia (hemoglobin \< 10 g/dl) or Thalassemia
* Carbon monoxide poisoning
* Acquired pathological or congenital disorders of the cerebral system, being clinically significant, respectively interfering in the investigator's opinion with the conduct of study
* Documented history of bleeding, clotting or coagulation disorders
* Patients who are not suitable for a CT perfusion
* Subjects who, in the opinion of the investigator, will be inappropriate for inclusion into this clinical investigation or will not comply with requirements of the study
* Any disorder in the investigator's opinion that could interfere with compliance of safety evaluation
* Pre-existing disability and/or legal representative
* Patients who are kept lawfully in an institution
* Participation in another interventional clinical investigation within the last 30 days before start of treatment
* History of, respectively diagnosis of pregnancy, or breastfeeding patients
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
75 Years
Study:
NCT03249220
Study Brief:
Protocol Section:
NCT03249220