Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 4:19 AM
Ignite Modification Date:
2025-12-25 @ 4:19 AM
NCT ID:
NCT01461720
Eligibility Criteria:
Inclusion Criteria:
* Experiences stroke onset within 2 weeks to 2 months
* NIHSS score of \>10-35
* Never received or failed thrombolysis
* Evidence of unilateral middle cerebral artery infarct on brain MRI
Exclusion Criteria:
* Medically unfit (eg. those are unstable haemodynamically despite treatment, with worsening conscious level and with other serious medical co-morbidity)
* Evidence of any tumor or other space-occupying lesion on brain MRI
* Evidence of hemorrhagic stroke on brain CT or MRI
* Experiences transient ischemic attack or lacunar infarct
* Has any acute or chronic infections such as Hepatitis B, Hepatitis C and HIV
* Is diagnosed with concurrent malignancy or primary hematological disorders
* Renal impairment indicated with serum creatinine greater than 200 umol/l or creatinine clearance less than 30 ml/min
* Liver impairment indicated with serum aspartate transaminase and serum alanine transaminase greater than 4 times upper limit of the normal range
* Any contraindication to stem cell transplantation or bone marrow biopsy
* Any co-morbidity which will compromise the ability to obtain adequate stem cells (eg. chronic debilitating diseases, frail patients and patients with known osteoporosis)
* Any contraindication to brain MRI (eg. metal implants, pacemaker, joint implants and ocular implants)
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
30 Years
Maximum Age:
75 Years
Study:
NCT01461720
Study Brief:
Protocol Section:
NCT01461720