Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 4:19 AM
Ignite Modification Date:
2025-12-25 @ 4:19 AM
NCT ID:
NCT06475820
Eligibility Criteria:
Inclusion Criteria:
following diseases:
* acute lymphoblastic,
* myeloblastic,
* biphenotypic,
* bilinear leukemia,
* malignant lymphoma,
* myelodysplastic syndrome, 2. Donors:
* voluntary fully HLA-matched unrelated,
* related haploidentical donors 3. Clinical center: National Medical Research Center of pediatric haematology, oncology and immunology named after Dmitry Rogachev" of the Ministry of Health of Russia 4. Availability of consent to conduct a study
Exclusion Criteria:
Age over 21 years
* Patients with ALL outside clinical and hematological remission
* Clinical status:
* Lansky/Karnowski index \<70% (supplement No.1)
* Heart function: left ventricular ejection fraction \<40% according to ultrasound of the heart1
* Kidney function: clearance of endogenous creatinine \< 70 ml / min
* Liver function: total bilirubin, ALT, AST, ALP \> 2 norms
* Lung function: lung capacity \<50%, for children who cannot carry out of respiratory function - oxygen saturation during pulse oximetry \<92%
* Uncontrolled viral, fungal or bacterial infection.
* Mental illness of the patient or caregivers, making it impossible to realize the essence of the study and compromising compliance with medical appointments and sanitary and hygienic regime 1 These patients may receive treatment according to the protocol, but the results will be evaluated separately
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
1 Day
Maximum Age:
21 Years
Study:
NCT06475820
Study Brief:
Protocol Section:
NCT06475820