Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 4:18 AM
Ignite Modification Date:
2025-12-25 @ 4:18 AM
NCT ID:
NCT01515020
Eligibility Criteria:
INCLUSION CRITERIA :
* Patients with nosocomial and/or healthcare-associated bacteremia with Gram-positive cocci in clusters
* Confirmed to be meticillin-resistant S. aureus using a GeneXpert rapid molecular test
* Aged 18 years or older
* Who have given their written consent when this is possible or someone from his/her family, or if not possible, emergency inclusion
* Who can receive follow-up for the entire duration of the study, i.e. 90 days
EXCLUSION CRITERIA :
* Known allergy to vancomycin or daptomycin
* Women who are pregnant or breast-feeding
* Patients who have received vancomycin treatment for more than 48 hours between the diagnostic blood culture and randomization
* Specific sites of infection: pneumonia, meningitis, brain abscess, osteitis, polymicrobial infection
* Life expectancy considered to be less than 72 hours
* Severe hepatic impairment (Child C)
* Short-term intravascular catheters which cannot be removed immediately
EXCLUSION CRITERIA between D1 and D5 inclusive :
* Specific sites of infection: osteitis diagnosed between D1 and D5 inclusive
* Permanent foreign material infection (endovascular stents, replacement heart valves or joints, pace maker etc.) which cannot be removed within 36 hours of the first dose of the study drug
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT01515020
Study Brief:
Protocol Section:
NCT01515020