Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 4:14 AM
Ignite Modification Date:
2025-12-25 @ 4:14 AM
NCT ID:
NCT03583320
Eligibility Criteria:
Inclusion Criteria:
1. Patients above 18 years of age with ischaemic sounding chest pain prompting visit to the emergency department (suspected ACS).
2. No-ischaemic ECG changes (i.e. no ST-segment elevation or depression 1mm in 2 or more contiguous leads, and/or T-wave inversions).
3. Episode of chest pain within last 12 hours.
4. Initial troponin in the intermediate range (5-50ng/L).
Exclusion Criteria:
1. STEMI.
2. Signs and symptoms of acute heart failure and/or haemodynamic instability.
3. Dynamic ischaemic ECG changes.
4. Patient not suitable to undergo CTCA
1. Inability to breath hold for 10 seconds
2. Severe renal impairment (eGFR \<30 mL/min)
3. Contraindication to beta-blockers (not relevant for patients with baseline sinus rhythm at rate of \<63bpm)
5. Atrial Fibrillation on ECG.
6. Patients with known significant obstructive coronary artery disease (\>50% stenosis) on previous invasive or CT coronary angiogram.
7. Patients with previous PCI/CABG revascularisation.
8. Patients with a history of congenital heart disease.
9. Patients with known coronary artery anomalies.
10. Patients who lack capacity to give consent or participate in the study.
11. Previous recruitment to the present study.
12. Known pregnancy or patients who are currently breast feeding.
13. Prisoners.
14. Patients involved in current or a recent (within the last 4 months) CTIMP trial.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT03583320
Study Brief:
Protocol Section:
NCT03583320