Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 4:14 AM
Ignite Modification Date:
2025-12-25 @ 4:14 AM
NCT ID:
NCT05629520
Eligibility Criteria:
Inclusion Criteria:
* Current diagnosis of MDD based on the MINI International Neuropsychiatric Interview (MINI)
* For treatment resistant depression participants: unsuccessful treatment with at least 2 types or doses of antidepressant medication treatment
* Right-handed
* Capacity for informed consent
* Score a 9 or higher on the MADRS
Exclusion Criteria:
* Comorbid Bipolar Disorder
* Substance use disorder in the last 12 months
* Schizophrenia, and other psychotic disorders
* Comorbid illness such as endocrinological illness (e.g. Cushing's disease) rheumatologic illness (e.g., systemic Lupus erythematosus, current treatment with glucocorticoids), and autoimmune diseases (e.g. psoriasis)
* Pregnancy
* Daily NSAID or aspirin use and any metallic implant
* Visual/Hearing Impairments that would keep participant from being able to complete tasks
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
65 Years
Study:
NCT05629520
Study Brief:
Protocol Section:
NCT05629520