Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 4:14 AM
Ignite Modification Date:
2025-12-25 @ 4:14 AM
NCT ID:
NCT01045720
Eligibility Criteria:
Inclusion Criteria:
1.20 year and older. All genders. 2.Psychiatry doctor diagnosed schizophrenia or schizoaffective disorder will be recruited for participation in this study.
3.Using clozapine as an antipsychotic drug and has a side-effect of hypersalivation.
4.Testee agree and sign informed consent forms to do this experiment.
Exclusion Criteria:
1. Use clozapine as an antipsychotic drug not over 8 weeks.
2. Testee have other diseases could influence saliva secretion, such as Parkinson's disease.
3. Pregnant, prepare to pregnant within half a year or in the lactation period.
4. Add or alter following medicines within 2 weeks:
4.1 Central acting 2-adrenergic receptor agonist 4.2 anticholinergic/antimuscarinic drugs 4.3 b-adrenoreceptor blockers, diphenhydramine, botulinum toxin injection
5. Testee's lever function test (AST/ALT) is higher than 3 (4 weeks medication).
6. Testee's kidney function test (Cr) is higher than 2.5mg/dl (4 weeks medication).
7. Testee have participate other medicine trial within one month.
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
20 Years
Study:
NCT01045720
Study Brief:
Protocol Section:
NCT01045720