Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 4:13 AM
Ignite Modification Date:
2025-12-25 @ 4:13 AM
NCT ID:
NCT03588520
Eligibility Criteria:
Inclusion Criteria:
* Age 18 years old or higher
* Stable CKD stage 3-4 (CKD-EPI estimated GFR: 15-60 ml/min/1.73m2)
* Treated or untreated uncontrolled hypertension, defined as office BP \>140/90 mmHg for patients with diabetic or non-diabetic CKD and protein excretion \<0.3 gr/day or office BP \>130/80 mmHg for patients with diabetic or non-diabetic CKD and protein excretion ≥0.3 gr/day.22-24
* Patients must provide informed written consent
Exclusion Criteria:
* End-stage renal disease under hemodialysis or peritoneal dialysis
* Known secondary cause of hypertension (i.e., pheochromocytoma, primary aldosteronism, renovascular hypertension)
* Chronic atrial fibrillation
* Hospitalization for acute myocardial infarction, unstable angina or acute ischemic stroke within the 3 previous months
* Severe congestive heart failure stage III-IV according to New York Heart Association (NYHA) classification
* Body mass index (BMI) of \>40 kg/m2
* History of malignancy or any other clinical condition associated with very poor prognosis
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT03588520
Study Brief:
Protocol Section:
NCT03588520