Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 4:09 AM
Ignite Modification Date:
2025-12-25 @ 4:09 AM
NCT ID:
NCT03176420
Eligibility Criteria:
Inclusion Criteria:
* Age ≥ 21
* Complete occlusion of cervical ICA on imaging studies (MRA or CTA) and confirmed with DSA
* History of TIA or stroke within 120 days of enrollment
* increased MTT on CTP in the ipsilateral side of the occluded ICA specifically in the MCA territory when compared to the opposite unaffected hemisphere
* All occlusion is due to atherosclerotic disease
* MoCA \< 26 but ≥23
Exclusion Criteria:
* History of Moyamoya or Moyamoya like disease
* Tandem occlusion
* No evidence of increased MTT on CT perfusion
* Severe co-morbid diseases: end-stage renal disease, liver cirrhosis, COPD requiring home oxygen, terminal illness such as cancer, Parkinson disease or other neurodegenerative diseases, severe cognitive heart failure, seizures, debilitating stroke, mRS ≥3.
* Short life expectancy due to cancer or other co-morbid diseases
* Class D on COICA classification
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
21 Years
Maximum Age:
90 Years
Study:
NCT03176420
Study Brief:
Protocol Section:
NCT03176420