Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 4:05 AM
Ignite Modification Date:
2025-12-25 @ 4:05 AM
NCT ID:
NCT07019402
Eligibility Criteria:
Inclusion Criteria:
* Aged 50 years or greater
* Capable of attending screening and assessment sessions and the internet-based intervention modules
* Fluent English speaker
* Corrected (near and far) visual acuity of 20/40 or better
* Adequate hearing for experimental purposes
* Absence of diagnosed terminal illness
* Absence of diagnosed neurological disorders
* No history of psychotic disorder or substance abuse disorder diagnosed by a psychologist or psychiatrist
* Absence of medication use that significantly alters brain activity
* No history of diagnosed learning disability that would interfere with the completion of the cognitive tasks
* Report elevated scores on the self-report Everyday Cognition (E-Cog)-39 subjective cognitive decline with normatively intact performance on cognitive testing (as determined by the neuropsychological battery)
* No evidence of mild cognitive impairment or dementia as assessed by the neuropsychological measures from the National Alzheimer's Coordinating Center (NACC) Uniform Data Set OR inadequate self-reported performance of instrumental activities of daily living
* Ability to engage in light stretching/movement-based activities with or without assistive devices
* Absence of any MRI contraindications
* Not pregnant and not attempting to become pregnant
* Absence of self-reported claustrophobia
* No regular practice of meditation or yoga (defined as once or more per week) AND No previous participation in a structured mindfulness class (e.g., Mindfulness-Based Stress Reduction, intensive meditation retreat)
* Access to internet and at-home computer with a working microphone and video
* Not enrolled in other RCTs examining the efficacy of exercise training, cognitive rehabilitation, stress management, progressive muscle relaxation or other health-based rehabilitation
Exclusion Criteria:
* Aged less than 50 years
* Any physical or pragmatic limitation that prohibits attendance of screening or assessment sessions, or intervention engagement
* No fluency in English
* Corrected (near or far) visual acuity worse than 20/40
* Self-reported hearing impairment that would affect ability to hear the experimenter
* Diagnosis of terminal illness
* Presence of diagnosed neurological disorders such as: Alzheimer's disease, Vascular Dementia, Parkinson's disease, Multiple Sclerosis, Traumatic Brain Injury, Fronto-Temporal Lobar Degeneration, Lewy Body Disease
* History of psychotic disorder or substance abuse disorder diagnosed by a psychologist or psychiatrist
* Medication use that significantly alters brain activity
* History of diagnosed learning disability that would interfere with the completion of the cognitive tasks
* Does not report subjective cognitive decline AND/ OR does not perform in the normatively intact range on neuropsychological testing
* Evidence of mild cognitive impairment (MCI) or dementia OR inadequate self-reported performance of instrumental activities of daily living
* Any physical limitation or pragmatic limitation that prohibits attendance at assessment sessions and intervention modules with or without assistive devices
* Presence of MRI contraindications as assessed through the MRI screening form.
* Pregnant or attempting to become pregnant
* Self-reported claustrophobia
* Any regular practice of meditation or yoga (defined as once or more per week) OR Previous participation in a structured mindfulness class (e.g., Mindfulness-Based Stress Reduction, intensive meditation retreat)
* No access to internet or at-home computer with a working microphone and video
* Current enrollment in other RCTs examining the efficacy of exercise training, cognitive rehabilitation, stress management, progressive muscle relaxation or other health-based rehabilitation
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
50 Years
Study:
NCT07019402
Study Brief:
Protocol Section:
NCT07019402