Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 4:04 AM
Ignite Modification Date:
2025-12-25 @ 4:04 AM
NCT ID:
NCT01879202
Eligibility Criteria:
Inclusion Criteria:
* Diagnosis of multiple sclerosis according to McDonalds criteria.
* Age \> 18 years
* Fatigue as measured by Fatigue Severity Scale
* Signed informed consent
Exclusion Criteria:
* Known allergy or hypersensitivity to Methylphenidate or any of its ingredients
* Marked anxiety, tension and agitation
* Patients with glaucoma or hyperthyroidism
* Patients with motor-tics, a family history or diagnosis of Tourette´s syndrome
* Treatment with monoamine oxidase inhibitors, also within a minimum of 14 days following discontinuation (hypertensive crisis may result).
* Phaeochromocytoma
* Pre-existing cardiovascular disorders including severe hypertension, angina, arterial occlusive disorder, heart failure, haemodynamically significant congenital heart disease, cardiomyopathies, myocardial infarction, potentially life-threatening arrhythmias and channelopathies.
* History of drug dependence or alcoholism
* History of seizures
* Pregnant women or females of childbearing potential who want to become pregnant within the study period.
* Severe psychiatric disorders
* Change of any medication treatment \<8 weeks before starting the study
* Participation in any other clinical trial at the same time
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT01879202
Study Brief:
Protocol Section:
NCT01879202