Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 4:04 AM
Ignite Modification Date:
2025-12-25 @ 4:04 AM
NCT ID:
NCT03371602
Eligibility Criteria:
Inclusion Criteria:
* Patient at least 18 years of age, male or female requiring abdominal or thoracic surgery or multi-organ sampling;
* Affiliated to a social security or similar system;
* Not subject to legal protection;
* Having given consent to participate in the study (or consent from the trusted person)
* Control group (C): non-septic mesocolic programmed abdominal or thoracic surgery: gastrectomy, esophagectomy, pancreatectomy, hepatectomy
* Sepsis group (S): Abdominal or thoracic surgery in a septic context (peritonitis, mediastinitis, pleural abscess)
* Group Mechanical Ventilation (MV): Patient in brain death for which a multi organ sample is planned
* Mechanical Ventilation + Sepsis (S-MV) group: Patient under controlled mechanical ventilation to undergo abdominal or thoracic surgery in a septic context (peritonitis, mediastinitis, pleural abscess)
Exclusion Criteria:
* Pregnant woman (diagnosis of interrogation)
* severe and / or unbalanced chronic respiratory disease; severe malnutrition
* Long-term corticosteroids\> 5mg / day for more than 1 month
* Myopathy
* surgery by laparoscopic
By group:
* Control group: Sepsis, preoperative controlled mechanical ventilation and preoperative hemodynamic instability
* Mechanical Ventilation Group: Sepsis, duration of controlled mechanical ventilation \<24 hours or\> 7 days
* Sepsis Group: Preoperatively controlled mechanical ventilation
* Mechanical Ventilation - Sepsis Group: duration of controlled mechanical ventilation \<24 hours or\> 7 days
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT03371602
Study Brief:
Protocol Section:
NCT03371602