Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 4:03 AM
Ignite Modification Date:
2025-12-25 @ 4:03 AM
NCT ID:
NCT04107402
Eligibility Criteria:
Inclusion Criteria:
* Informed consent of patients, their relatives or independent physician
* Septic shock defined as a sepsis with vasopressor therapy needed to elevate MAP ≥65 mmHg, and lactate \> 2 mmol/L, despite adequate fluid resuscitation of 30mL/kg of intravenous crystalloid within 6 hours. Inclusion within 48 hours of ICU admission.
* Covid-19 patients with ARDS and PaO2/FiO2 \< 200. Inclusion within 5 days after ICU admission.
Exclusion Criteria:
* Patients on therapeutic anticoagulation therapy (oral or parenteral) including heparins, fondaparinux, vitamin K antagonist, novel oral anticoagulants, for any reasons DESPITE therapeutic anticoagulation as a treatment for Covid-19 patients.
* Recent (less than 1 month) chemotherapy
* Active inflammatory disease
* Haemophilia and other coagulopathy
* Previous history of thrombocytopenia (\<100 000 platelets/mm3)
* Cirrhosis (Child Plug \> A)
* Recent (less than 48 hours) major surgery
Exclusion criteria for Covid-19 patients:
\- bacterial co-infection
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT04107402
Study Brief:
Protocol Section:
NCT04107402