Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 4:03 AM
Ignite Modification Date:
2025-12-25 @ 4:03 AM
NCT ID:
NCT07270302
Eligibility Criteria:
Inclusion Criteria:
* Age 18 or older that meet diagnostic criteria for CRS with or without polyposis as documented by their recruiting physician.
* Diagnostic criteria for CRS will be defined according to EPOS criteria of \>12 weeks of 2 of the following subjective symptoms: nasal blockage or obstruction, rhinorrhea, hyposmia, or facial pain/pressure AND objective evidence of CRS on either nasal endoscopy or CT scan
Exclusion Criteria:
* Patients who have previously undergone sinus surgery
* Severe polyposis; defined as Lund Kennedy endoscopy score greater than 1
* Patients who are currently using or who have previously used biologic medications for their nasal polyps. These medications include: dupilumab, omalizumab, mepolizumab, tezepelumab, or depemokimab
* Inability to complete surveys in English
* known comorbid mucociliary disease
* known adrenal disease or other HPA dysfunction
* patients taking oral corticosteroids for other medical conditions
* oral antibiotic administration within 2 weeks of study participation
* a baseline SNOT-22 score less than 9, due to inability to achieve the MCID
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT07270302
Study Brief:
Protocol Section:
NCT07270302