Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 3:56 AM
Ignite Modification Date:
2025-12-25 @ 3:56 AM
NCT ID:
NCT03929302
Eligibility Criteria:
Inclusion Criteria: Eligible participants will be:
* Ages 55-85 years
* At least 12 years of education
* Right hand dominant
* With or without minor memory complaints (those with a diagnosis of Alzheimer's disease,
* Participants who can safely have an MRS scan
* Have motor abilities including the use of the right arm and hand for neuropsychological testing.
* Able to speak, read, and comprehend English fluently
* Non-pregnant, and not on Hormone replacement therapy
Exclusion criteria will be:
* Pregnancy
* Use of Hormone Replacement therapy
* Less than 12 years of education
* Left hand dominant
* Unable to speak, read and write English fluently (Testing and training material are validated in English).
* Neurological Disorders, e.g., stroke, brain tumor, cerebral hemorrhage.
* Autoimmune disorders like fibromyalgia, systemic lupus erythematosus (SLE), Multiple sclerosis and rheumatoid arthritis.
* Metabolic diseases such as diabetes mellitus, thyroid disorders that are not currently managed by a physician
* Psychiatric disorders such as bipolar disorder, major depressive disorder, pervasive developmental disorder, schizophrenia, anxiety disorder.
* Current drug or alcohol abuse
* Head injuries with an Ohio State University TBI Identification (Short Form) score greater than 3.
* Cancer treated with radiation and/or chemotherapy
* General anesthesia within the prior six months
* Uncorrected vision and hearing problems.
* Active pain requiring treatment
* BMI ≥35
* Previously diagnosed sleep disorders
* Known chronic obstructive pulmonary disease(COPD)
* Exclusion for imaging criteria (includes the following, or any other concerns by the AIRC staff)
* Permanent Makeup.
* Exclusions for metal safety include questionable ferrous implants, bullets, BB's, shrapnel,
* Medical devices which are unsafe in MRI.
* Hearing aid that cannot be removed.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
55 Years
Maximum Age:
85 Years
Study:
NCT03929302
Study Brief:
Protocol Section:
NCT03929302