Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 2:43 PM
Ignite Modification Date:
2025-12-24 @ 2:43 PM
NCT ID:
NCT05697159
Eligibility Criteria:
Inclusion Criteria:
Patients with moderate to severe active RA who have been prescribed filgotinib in line with the Summary of Product Characterisation and are:
* Adults ≥18 years \< 75 years.
* Right-handed (to reduce neuroimaging heterogeneity).
Exclusion Criteria:
* Inability to provide written informed consent.
* Severe physical impairment (e.g. blindness, deafness, paraplegia).
* Pregnant or breast feeding.
* Severe claustrophobia precluding MRI.
* Contraindications to MRI.
* Major confounding neurological disease including MS, Stroke, Traumatic Brain Injury.
* Previous targeted synthetic (e.g. baricitinib, tofacitinib) DMARD exposure for RA.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
74 Years
Study:
NCT05697159
Study Brief:
Protocol Section:
NCT05697159