Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 3:48 AM
Ignite Modification Date:
2025-12-25 @ 3:48 AM
NCT ID:
NCT05706402
Eligibility Criteria:
Inclusion Criteria:
1. Aged 40 years or above, either male or female.
2. Patients who are current or ex-smokers
* Ever-smoker is defined as having smoked at least one cigarette, pipe, water pipe, cigars, or hand rolled cigarettes a day for 1 or more years.
3. Patients with a pre-existing diagnosis of COPD admitted to the general medical and respiratory subspecialty wards for acute COPD exacerbation
* COPD is defined as dyspnoea and/or chronic productive cough with spirometry confirmation of persistent airflow limitation at FEV1/FVC less than 70%.
* COPD acute exacerbation is defined as an acute increase in symptoms (one or more of the following: cough frequency and severity, sputum production, dyspnoea) beyond normal day-to-day variations leading to a change in medication.
4. Patients who consent to join this clinical trial
Exclusion Criteria:
1. Patients who are on long-term NAC treatment
2. Patients who are not able to take NAC including drug allergy
3. Patients with other co-existing respiratory diseases including but not limited to asthma, interstitial lung diseases, and bronchiectasis
4. Patients on non-invasive or invasive mechanical ventilation where oral medication is not allowed
5. Patients on long term macrolide treatment
6. Patients on macrolide as antibiotics for COPD exacerbation
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
40 Years
Study:
NCT05706402
Study Brief:
Protocol Section:
NCT05706402