Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 3:45 AM
Ignite Modification Date:
2025-12-25 @ 3:45 AM
NCT ID:
NCT00037102
Eligibility Criteria:
To be eligible for entry into this study, candidates must meet the following eligibility criteria at the time of enrollment:
* Between the ages of 18 and 60 years, inclusive.
* Diagnosis of clinically definite relapsing MS.
* Must have been on AVONEX® therapy for at least six months.
* Brain MRI scans demonstrating lesions consistent with MS.
* Subject must have had at least one clinical exacerbation in the last year, and this must have occurred after having been on AVONEX® therapy for at least six to twelve (6-12) months. A clinical exacerbation is defined as a decrease of 0.1 in the MSFC composite or any of the subset domains scores administered 3 months apart.
* Give written informed consent prior to any testing under this protocol, including screening tests and evaluation that are not considered part of the subject's routine care.
To be eligible for treatment with methotrexate, subjects must have evidence for MS disease activity on their baseline screening MRI.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
60 Years
Study:
NCT00037102
Study Brief:
Protocol Section:
NCT00037102