Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 3:45 AM
Ignite Modification Date:
2025-12-25 @ 3:45 AM
NCT ID:
NCT03532802
Eligibility Criteria:
Inclusion Criteria:
* Wall thickness ≥ 15 mm in one or more myocardial segments that is not explained by loading conditions.
* LVOT gradient \> 30 mmHg at rest and/or \> 50 mmHg at Valsalva's maneuver or exercise
* New York Heart Association Functional class (NYHA) ≥ II
Exclusion Criteria:
* Age \< 18 years
* Known allergy to trial medicine
* Contraindications to beta-blocker treatment
* Contraindications to Magnetic resonans scan, including contraindication to the contrast agent gadolinium.
* Female patients who are pregnant (positive plasma-HCG), breastfeeding or of child-bearing potential while not practicing effective chemical contraceptive hormones.
* In case of patients having a pacemaker, they may not be pace-dependent.
* Treatment with Amiodarone
* Atrial fibrillation/flutter at the time of examination
* Bradycardia \< 49 beats/min
* Systolic blood pressure \< 100 mmHg
* Trifascicular block
* Previous transcoronary ablation of septum hypertrophy (TASH) or myectomy
* Current abuse of alcohol and/or drugs
* Significant co-morbidity or issues that makes the patient unsuitable for participation, judged by the investigator
* Patients who cannot give valid consent (e.g. mental illness or dementia)
* Patients who do not understand danish
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT03532802
Study Brief:
Protocol Section:
NCT03532802