Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 3:45 AM
Ignite Modification Date:
2025-12-25 @ 3:45 AM
NCT ID:
NCT07053202
Eligibility Criteria:
Inclusion Criteria:
* Age \>18 years;
* Diagnosis of HCC according to the Diagnosis and Treatment Guidelines for Primary Liver Cancer (2024 Edition), confirmed by pathological examination;
* Barcelona Clinic Liver Cancer (BCLC) stages A, B, and C, with non-resectable tumors;
* Liver function graded as Child-Pugh A or B;
* At least one measurable lesion according to the Response Evaluation Criteria in Solid Tumors (RECIST) 1.1;
* Eastern Cooperative Oncology Group (ECOG) performance status score of 0-2;
* No severe hematologic abnormalities or immune deficiencies;
* Expected survival time \>6 months.
Exclusion Criteria:
* Recurrent liver cancer or metastatic cancer from other organs;
* Previous treatment with other antitumor therapies, including surgery, radiotherapy, chemotherapy, targeted therapy, or immunotherapy;
* History of other malignant tumors;
* Pregnant or lactating women;
* Human immunodeficiency virus (HIV) infection;
* Severe cardiovascular, pulmonary, cerebral, or renal diseases;
* Active bleeding or coagulopathy outside the liver;
* Enrollment in another clinical trial or participation in a clinical trial within one month prior to admission;
* Psychiatric disorders or unstable mental status;
* Allergic reactions to the study drugs;
* Severe gastrointestinal diseases, such as active ulcers, or other conditions affecting drug absorption.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT07053202
Study Brief:
Protocol Section:
NCT07053202