Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 3:44 AM
Ignite Modification Date:
2025-12-25 @ 3:44 AM
NCT ID:
NCT02951702
Eligibility Criteria:
Inclusion Criteria:
* "High-risk" patients defined as: age older than 65, on gastric acid suppression, and select antibiotics
* Gastric acid suppression includes proton pump inhibitors and histamine-2 receptor antagonists
* Selected antibiotics include fluoroquinolone (ciprofloxacin, levofloxacin), clindamycin, a 3rd or 4th generation cephalosporin, a broad-spectrum aminopenicillin (ampicillin-sulbactam, piperacillin-tazobactam), or a carbapenem
Exclusion Criteria:
* Failure to meet all three requirements for "high risk"
* Vancomycin allergy
* Active clostridium difficile infection prior to inclusion
* Prophylactic oral vancomycin prior to study inclusion (i.e. prolonged vancomycin taper)
* Receipt of medications that also treat Clostridium difficile (metronidazole, rifaximin, fidaxomicin)
* Pregnant or breastfeeding
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
65 Years
Study:
NCT02951702
Study Brief:
Protocol Section:
NCT02951702