Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 3:44 AM
Ignite Modification Date:
2025-12-25 @ 3:44 AM
NCT ID:
NCT04539002
Eligibility Criteria:
Inclusion Criteria:
* Physician-confirmed diagnosis of MS based on the 2017 McDonald criteria
* 18-64 years old
* Have access to the internet and a device that can access virtual visits
* (Inclusion criteria to advance to clinical trial) Somatosensory evoked potential (SSEP) latency z-score ≥2 for P40 or inter-side difference in z-score ≥2 for P40
Exclusion Criteria:
* Medical or biophysical conditions that prohibit the use of a cycle ergometer or treadmill (medical readiness to be assessed by the Activity Readiness Questionnaire (PAR-Q)) or achievement of target heart rate.
* Engages in \>30 minutes/week of aerobic activity regularly.
* Clinically confirmed MS relapse in the last 3 months.
* Changes in disease modifying therapy (DMT) for MS in the last 6 months.
* Pregnant women.
* Treatment with steroids for MS in the last 30 days.
* Concurrent use of 4-aminopyridine or dalfampridine (medications which can alter SSEP) and unwilling to discontinue it for 2 days prior to SSEP testing.
* Have a known history of severe spinal canal stenosis
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
64 Years
Study:
NCT04539002
Study Brief:
Protocol Section:
NCT04539002