Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 3:32 AM
Ignite Modification Date:
2025-12-25 @ 3:32 AM
NCT ID:
NCT02946905
Eligibility Criteria:
Inclusion Criteria:
1. Age 18 and above
2. Able to provide informed consent
For Non-SCD :
1. Between age 18 and 55
2. Able to provide informed consent
3. Are age, race, and gender matched to a Sickle Cell Disease study subject.
Exclusion Criteria:
1. Age less than 18 years
2. Current pregnancy or lactation
3. Any medical condition that may result in neurocognitive or brain dysfunction that is not secondary to SCD including:
1. Diabetes mellitus
2. Coronary artery disease
3. Peripheral vascular disease
4. Other causes of cerebral vasculitis such as Systemic Lupus Erythematosus (SLE)
4. Any contraindication to MRI scanning including:
1. History of claustrophobia
2. Presence of metallic implants such as cardiac pacemaker or implantable defibrillator, surgical aneurysm clips, or any implanted device (e.g. insulin pump, drug infusion device)
3. Any known metal fragments embedded in the body (eg: ear implant)
4. Neural stimulator (e.g. Transcutaneous Electrical Nerve Stimulation Unit)
5. Metal in the eye (e.g. from machining)
6. Any metallic foreign body, shrapnel, or bullet
7. Inability to lie still for 30 minutes or more
5. Inability to provide direct consent
6. In a current medical or pain crisis as diagnosed by attending physician -
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT02946905
Study Brief:
Protocol Section:
NCT02946905