Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 3:32 AM
Ignite Modification Date:
2025-12-25 @ 3:32 AM
NCT ID:
NCT01574105
Eligibility Criteria:
Inclusion Criteria:
* Patients scheduled for elective or urgent CABG of two to six vessels.
Exclusion Criteria:
* Preoperative:
* Hemoglobin of less than 110grams/Litre
* Under 18 years of age
* Mass less than 75 kilograms
* Presence of an intra-aortic balloon pump
* Emergency surgery, requiring operative intervention within 24 hours of consultation to the cardiac surgery team
* Need for cardiac surgical intervention in addition to planned CABG (with the exception of patent foramen ovale closure)
* Ejection fraction of less than 50%, as determined by echocardiogram or angiography
* Pulmonary hypertension with pulmonary artery pressures greater than 60mmHg
* Presence of infectious endocarditis
* Hepatic failure with impaired liver function, including INR greater than 1.5 Known diagnosed bleeding disorder
* History of heparin induced thrombocytopenia and thrombosis
* Renal failure with pre-operative creatinine greater than 200ml/min or oliguria with urine output less than 10millilitres/hour
* Allergy to tranexamic acid
* Pregnancy
Intraoperative:
* Discovery of infectious endocarditis
* Need for cardiac surgical intervention in addition to planned coronary CABG
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
40 Years
Maximum Age:
85 Years
Study:
NCT01574105
Study Brief:
Protocol Section:
NCT01574105