Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 3:30 AM
Ignite Modification Date:
2025-12-25 @ 3:30 AM
NCT ID:
NCT02428205
Eligibility Criteria:
Inclusion Criteria:
* Diagnosis of autism spectrum disorder (ASD), defined in this study by the DSM-V criteria plus Autism Diagnostic Observation Schedule (ADOS) criteria for Autism.
* Aged 3-8
* Participants must also be enrolled in an early behavioral intervention program at the Thompson Center or another institution in Missouri for the duration of the study.
Exclusion Criteria:
* Non-autism learning disability (e.g. dyslexia)
* Major psychiatric diagnosis (e.g. major depression, schizophrenia, bipolar disorder)
* Other neurological diagnosis
* Major head trauma
* Any of the following exclusionary criteria related to propranolol (diabetes, reactive airway/pulmonary disease, thyroid disease, bradyarrhythmias, unexplained syncope, narrow angle glaucoma, known hypersensitivity/adverse reaction to beta-blockers, potentially interacting drugs, underweight \< 15 kg)
* Any of the following exclusionary criteria related to the use of electrocardiogram (history of rash from adhesives)
* Any of the following exclusionary criteria related to the pupillary reflex measurement (uncorrectable visual acuity impairment).
* Participants with a heart rate of less than 60 or a systolic blood pressure of less than 75 at the outset of the study will be excluded.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
3 Years
Maximum Age:
10 Years
Study:
NCT02428205
Study Brief:
Protocol Section:
NCT02428205