Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 3:30 AM
Ignite Modification Date:
2025-12-25 @ 3:30 AM
NCT ID:
NCT00255905
Eligibility Criteria:
Inclusion Criteria:
* History of recurrent depression with the age of onset between 20 and 40 years of age
* At least one depressive episode within 2 years prior to study entry
* At least three discrete depressive episodes within 10 years prior to study entry
* Successful treatment for or resolution of last episode of depression
* Participants whose depression is in remission are eligible for study enrollment. Criteria for remission includes more than 3 consecutive weeks during which the patient does not meet DSM-IV criteria for depression; a Hamilton Rating Depression Scale score less than 6 and a Beck Depression Inventory (BDI) less than 6; no feelings of depression for at least 6 months prior to study entry; and have not taken depression medication for at least 3 months prior to study entry. Once enrolled in the study, these participants must score less than 6 on the weekly BDIs for the first 3 weeks of the study.
* Have experienced mental stability between depressive episodes
* Willing to discontinue over-the-counter or naturopathic remedies for insomnia or depression during the study
* Able to write and speak English fluently
Exclusion Criteria:
* Current use of maintenance antidepressant therapy
* History of a failure to respond to citalopram treatment
* Unstable medical or psychiatric illness other than major depressive disorder
* History of seizures or head injury
* Current substance or alcohol abuse
* Symptoms suggestive of sleep disorders other than insomnia
* Pregnancy or plan to become pregnant within 2 years of study entry
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
25 Years
Maximum Age:
65 Years
Study:
NCT00255905
Study Brief:
Protocol Section:
NCT00255905