Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 3:29 AM
Ignite Modification Date:
2025-12-25 @ 3:29 AM
NCT ID:
NCT03695705
Eligibility Criteria:
Inclusion Criteria:
1. Low Ascitic fluid protein level \<1gm/dl
2. Advanced liver disease as evidenced by CTP≥9
3. Serum billirubin≥3 mg/dl
4. Impaired renal function defined by serum creatinine≥1.2 mg/dl
5. Blood urea nitrogen 25mg/dl
6. Serum sodium level≤ 1.2 meq/l
Exclusion Criteria:
1. Inability to obtain informed consent from patient or relatives.
2. Acute on chronic liver failure
3. Severe cardiopulmonary disease
4. Pregnancy
5. Age \<18yrs
6. Post liver transplant patients
7. HIV infection
8. Recent abdominal surgery(with in last 6 months)
9. Portal vein thrombosis
10. Splenectomy
11. Patient on immunosuppressive drugs except for alcoholic steatohepatitis
12. Patients on psychoactive drugs, such as antidepressants or sedatives
13. Hypersensitivity to norfloxacin and rifaximin
14. Malignancies including Hepatocellular carcinoma
15. Prior history of hepatic encephalopathy on Rifaximin -
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT03695705
Study Brief:
Protocol Section:
NCT03695705