Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 3:28 AM
Ignite Modification Date:
2025-12-25 @ 3:28 AM
NCT ID:
NCT00487305
Eligibility Criteria:
Inclusion Criteria:
* Histologically confirmed follicular lymphoma
* Patients with relapsed follicular lymphoma achieving at least a PR following their most recent systemic chemotherapy and/or immunotherapy regimen.
* Lymphoma accessible for sampling or existing cryopreserved lymphoma tumor judged suitable for vaccine preparation.
* 4 weeks must have elapsed between the completion of the the last chemotherapy, immunotherapy, glucocorticoid therapy, radiotherapy, or experimental therapy.
* ECOG Performance Status 0 or 1
* Estimated life expectancy of \> 6 months
* 35 years of age or older
* Adequate recovery of drug related toxicities, surgery or radiation therapy
* Greater than 6 months since autologous stem cell transplantation
* Laboratory parameters as outlined in the protocol
Exclusion Criteria:
* Uncontrolled active infection or illness
* Psychiatric illness/social situation that would limit study compliance
* Pregnancy or nursing mothers
* Evidence of infection with HIV or viral hepatitis
* Other invasive malignancy
* Existing autoimmune cytopenia
* Previous allogeneic stem cell transplant
* Pre-existing autoimmune disease requiring anti-inflammatory therapy
* Participation in previous vaccine trial
* Any component of grade 3 follicular lymphoma or transformed follicular lymphoma
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
35 Years
Study:
NCT00487305
Study Brief:
Protocol Section:
NCT00487305