Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 3:28 AM
Ignite Modification Date:
2025-12-25 @ 3:28 AM
NCT ID:
NCT02025205
Eligibility Criteria:
Inclusion Criteria:
* Homogeneous emphysema
* 15% ≤ FEV1 ≤ 45% predicted
* TLC \> 100% predicted
* RV ≥ 200% predicted
* 6MWT ≥ 150 m
* Non-smoker \> 8 weeks prior to study entry
* Absence of Collateral Ventilation in the target lobe
Exclusion Criteria:
* Active pulmonary infection
* More than 3 exacerbations with hospitalizations over the past 12 months
* Pulmonary hypertension (sPAP \> 45 mmHg)
* MI or other relevant CV events in the past 6 months
* Alpha-1 antitrypsin deficiency
* Bronchiectasis
* Prior LVR or LVRS procedure
* \> 20% difference in perfusion between right and left lung
* Hypercapnia (paCO2 \> 55 mmHg
* Asthma
* Use of more than 25 mg/day prednisolone or equivalent
* Severe bullous emphysema
* Systemic or malignant disease with high death probability within 12 months
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
40 Years
Study:
NCT02025205
Study Brief:
Protocol Section:
NCT02025205