Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 3:28 AM
Ignite Modification Date:
2025-12-25 @ 3:28 AM
NCT ID:
NCT00062205
Eligibility Criteria:
DISEASE CHARACTERISTICS:
* Diagnosis of Ewing's family of tumors OR desmoplastic small round-cell tumor
* Must have immunohistochemical evidence of expression of greater than 2+/4+ for either Kit (CD117) or platelet-derived growth factor receptor -a or -b
* No symptomatic brain metastases
* Asymptomatic brain metastases are allowed provided patient is not on concurrent anticonvulsants or corticosteroids
PATIENT CHARACTERISTICS:
Age
* Over 16
Performance status
* ECOG 0-2
Life expectancy
* Not specified
Hematopoietic
* Absolute neutrophil count greater than 1,500/mm\^3
* Platelet count greater than 100,000/mm\^3
* Hemoglobin greater than 9 g/dL
Hepatic
* Bilirubin less than 1.5 times upper limit of normal (ULN)
* SGOT and SGPT less than 2.5 times ULN
* No chronic active hepatitis
* No cirrhosis
* No other acute or known chronic liver disease
Renal
* Creatinine less than 1.5 times ULN
Cardiovascular
* No concurrent poorly controlled or severe cardiovascular disease
Pulmonary
* No concurrent poorly controlled or severe pulmonary disease
Other
* HIV negative
* No concurrent poorly controlled or severe central nervous system disease
* No other concurrent poorly controlled or severe nonmalignant disease
PRIOR CONCURRENT THERAPY:
Biologic therapy
* Not specified
Chemotherapy
* At least 3 weeks since prior chemotherapy
Endocrine therapy
* See Disease Characteristics
Radiotherapy
* At least 3 weeks since prior radiotherapy
Surgery
* More than 2 weeks since prior major surgery
Other
* More than 28 days since prior investigational agents
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
16 Years
Study:
NCT00062205
Study Brief:
Protocol Section:
NCT00062205