Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 3:27 AM
Ignite Modification Date:
2025-12-25 @ 3:27 AM
NCT ID:
NCT02441205
Eligibility Criteria:
Inclusion Criteria:
* Age 65-80 years
* Prediabetic - Fasting plasma glucose is 100 - 125 on two separate days
* Able to walk for 2 minutes or more without stopping
* LDL Cholesterol ≤ 190; Triglycerides \< 600;
* Blood Pressure ≤ 160/90
* Inactive: Exercise \< 2 days per week
* Medications: Stable use of all medications ≥ three months
Exclusion Criteria:
* Smoker: tobacco use within the last 12 months
* Dieting or intending to diet; not weight stable ≥ six months (weight change \< 5 pounds)
* Use of confounding inflammatory medications: aspirin, ibuprofen, naproxen (NSAIDS - nonsteriodal anti-inflammatory drugs)
* History of diabetes, heart disease or taking medications for those conditions
* History of hypertension (high blood pressure) not controlled with medication
* Unwillingness to undergo muscle biopsies and all other study testing, or to continuously participate in exercise training for 12 weeks.
* Inability to give blood continuously through a catheter (please notify the study nurse of any difficulties you have had in the past when having your blood drawn; the study nurse will determine whether you are excluded for this reason)
* Unwillingness to conduct ALL exercise sessions at the fitness facility during research study staff supervised times.
* Orthopedic limitations, musculoskeletal disease and/or injury Due to the nature of the study, persons with known joint, muscle or other orthopedic limitations that restrict physical activity may be excluded.
* Able to decide if you want to take part in the study
* Lack of transportation to the exercise and testing facilities
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
65 Years
Maximum Age:
80 Years
Study:
NCT02441205
Study Brief:
Protocol Section:
NCT02441205