Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 2:38 PM
Ignite Modification Date:
2025-12-24 @ 2:38 PM
NCT ID:
NCT05014659
Eligibility Criteria:
Inclusion Criteria:
* both male and female
* 50-64 years old
* no restrictions based on race, ethnicity, or socioeconomic status
* sedentary individuals (\<20 minutes; \<3 days/wk. physical activity)
* post-menopausal women (has experienced 12 consecutive months without menstruation for \>5 years).
Exclusion Criteria:
* \<50 or ≥65 years of age
* Subjects participating in regular exercise (\>20 min/day, \>3 days/week)
* female subjects who are pregnant, lactating or 1 month post-partum
* currently consuming or had consumed creatine supplementation \<1 month prior to screening
* currently consuming or consumed nitric oxide supplementation \<1 month prior to screening
* currently consuming or had consumed Vitamin C supplementation \<2 weeks prior to screening
* individuals who report chronic infections
* individuals reporting paralysis due to stroke
* individuals reporting advanced Parkinson's disease
* individuals reporting severe rheumatoid arthritis or other serious orthopedic problems that would prevent performance of the exercise tasks
* individuals currently taking medications that may affect central or peripheral circulation
* individuals with known cardiovascular and/or metabolic disease
* current smokers or those who quit \<6 months prior to screening
* individuals with hypercholesterolemia (total cholesterol \> 200mg/dL, high density lipoprotein \<40 mg/dL, low density lipoprotein \>130mg/dL)
* individuals with hypertension (systolic blood pressure \> 150 mmHg and/or diastolic blood pressure \>95mmHg).
* individuals with known kidney disease
* individuals with known liver disease
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
50 Years
Maximum Age:
64 Years
Study:
NCT05014659
Study Brief:
Protocol Section:
NCT05014659