Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 3:26 AM
Ignite Modification Date:
2025-12-25 @ 3:26 AM
NCT ID:
NCT02868905
Eligibility Criteria:
Inclusion Criteria:
Group 1:
* 18-50 year old women, age- (10 years) and sociocultural-matched with group 2
* Non obese and never been obese
* 18.5 \< BMI \< 25
* Folstein MMS \> 27
* Informed consent
* Affiliation to social security plan
Group 2:
* 18-50 year old women, age- (10 years) and sociocultural-matched with group 1
* Waist size \> 88cm
* 30 \< BMI \< 45
* Insulin-resistant patients (Insulin resistance index, HOMA-IR \> 3.8)
* Obesity onset during childhood (pre-puberty period)
* Folstein MMS \> 27
* Informed consent
* Affiliation to social security plan
Group 3:
* \>60 year old women, age- (10 years) matched with group 4
* No obesity history (18.5 ≤ BMI \< 25 at adult age)
* Sporadic forms of mild to moderate AD with demonstration of AD physiopathologic process according to new recommendations of 2011 of National Institute on Aging and Alzheimer's Association on diagnostic guidelines for Alzheimer's disease
* 15\< Folstein MMS ≤ 26
* Informed consent
* Affiliation to social security plan
Group 4:
* \>60 year old women, age- (10 years) matched with group 3
* Obesity history (BMI \> 30 at least one time at adult age)
* Sporadic forms of mild to moderate AD with demonstration of AD physiopathologic process according to new recommendations of 2011 of National Institute on Aging and Alzheimer's Association on diagnostic guidelines for Alzheimer's disease
* 15 \< Folstein MMS ≤ 26
* Informed consent
* Affiliation to social security plan
Exclusion Criteria:
Group 1:
* \<18
* Patient under guardianship, curatorship or judicial protection
* Folate supplementation
* Diabetic or glucose intolerant subjects
* Present participation to another study with neuropsychological evaluation and/or drug administration
* Pregnant women
Groups 2,3 and 4:
* \<18
* Patient under guardianship, curatorship or judicial protection
* Folate supplementation
* Present participation to another study with neuropsychological evaluation and/or drug administration
Group 2:
\- Pregnant women
Group 4:
\- Obese or overweight patients (BMI\>25)
Healthy Volunteers:
True
Sex:
FEMALE
Minimum Age:
18 Years
Study:
NCT02868905
Study Brief:
Protocol Section:
NCT02868905