Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 3:24 AM
Ignite Modification Date:
2025-12-25 @ 3:24 AM
NCT ID:
NCT03530605
Eligibility Criteria:
Inclusion Criteria:
* Histological de novo diagnosis of PCNSL
* Tumor located in the supra-tentorial brain region
* Karnofsky performance score of 70 or above
* Ineligible for chemotherapy due to age or other co-morbidities
* Life expectancy of at least 3 months
* Patient has a caretaker willing to assist with study compliance
* Patient is able to provide written consent on their own behalf
Exclusion Criteria:
* Second or subsequent recurrence of PCNSL
* Patient wishes to receive systemic treatment
* Implanted electronic medical device in the brain (deep brain stimulator, vagus nerve stimulator, programmable shunt, etc.)
* Skull defect without replacement
* Prior radiation, surgery, or chemotherapy for PCNSL within the 4 weeks prior to enrollment
* Patient unable to comply with Optune device treatment or the study follow- up schedule
* Active participation in another therapeutic clinical trial
* Patient unable to provide written consent on their own behalf
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
70 Years
Study:
NCT03530605
Study Brief:
Protocol Section:
NCT03530605