Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 3:24 AM
Ignite Modification Date:
2025-12-25 @ 3:24 AM
NCT ID:
NCT01730105
Eligibility Criteria:
* INCLUSION CRITERIA:
* Male
* Between 18-40 years old
* Willing to participate and provide informed consent
EXCLUSION CRITERIA:
* Hypo- or hyper-thyroid (history or TSH greater than 5.0 or less than 0.4 milli-international units per liter)
* Blood pressure greater than 140/90 millimeters of mercury (19) or current antihypertensive therapy
* History of cardiovascular disease
* BMI less than or equal to 20 or greater than or equal to 25 kilogram per cubic meter
* Diabetes mellitus or impaired fasting glycemia (fasting serum glucose greater than 100 grams per liter).
* Hypercholesterolemia (serum greater than or equal to 240 levels grams per liter), hypertriglyceridemia (plasma greater than or equal to 220 levels grams per liter) and/or use of antilipemic therapy.
* Liver disease or ALT serum level greater than two fold the upper laboratory reference limit.
* Iron deficiency (Ferritin less than 40 nanograms per milliliter males) (20).
* Renal insufficiency or estimated creatinine clearance less than 50 milliliter per minute (MDRD equation).
* Claustrophobia.
* History of illicit drug or alcohol abuse within the last 5 years; current use of drugs (by history) or alcohol (CAGE greater than 3).
* Psychiatric conditions or behavior that would be incompatible with safe and successful participation in this study
* Current use of medications/dietary supplements/alternative therapies known to alter thyroid function.
* Current use of antiplatelet or anticoagulants.
* Allergy to lidocaine.
* Current smoker or user of tobacco products
* Current participation in weight loss programs (dietary, exercise or pharmacological) or more than 3 kg weight changes in last 6 months
* Spending greater than 70% daily hours outdoors
Healthy Volunteers:
False
Sex:
MALE
Minimum Age:
18 Years
Maximum Age:
40 Years
Study:
NCT01730105
Study Brief:
Protocol Section:
NCT01730105