Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 3:22 AM
Ignite Modification Date:
2025-12-25 @ 3:22 AM
NCT ID:
NCT04882605
Eligibility Criteria:
COHORT 1 = Matched Sibling Donors couples (MSD couples) INCLUSION CRITERIA
* recipient of HSCT selected from the French national database CRYOSTEM
* adult patients (18-50 years old)
* transplanted in first remission
* receiving myeloablative conditioning without anti-thymoglobulin
* 16 couples without any sign of GVH (8 males and 8 females)
* 16 couples with aGVH without cGVH
* 9 couples with cGVH without aGVH
* 9 couples with both cGVH and aGVH. EXCLUSION CRITERIA
* insufficient DNA material after Miltenyi extraction
COHORT 2 = Haploidentical couples INCLUSION CRITERIA
* patient undergoing a haploidentical HSCT in the Hematology Department of Nancy's University Hospital, Lorraine, France (French Minister registration number : DC-2020-4068) EXCLUSION CRITERIA
* insufficient DNA material after Miltenyi extraction (7 MSD couples)
Healthy Volunteers:
False
Sex:
ALL
Study:
NCT04882605
Study Brief:
Protocol Section:
NCT04882605