Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 2:35 PM
Ignite Modification Date:
2025-12-24 @ 2:35 PM
NCT ID:
NCT04216459
Eligibility Criteria:
Inclusion Criteria:
* Adult trauma patients admitted to ICU within 24 hours from trauma onset with injury severity score (ISS) ≥ 16 will be recruited after obtaining informed consent
Exclusion Criteria:
* • Patients admitted to ICU after time exceeding 24 hours from trauma onset.
* Patients whose age is less than 18 years.
* Pregnant female.
* Breast feeding women.
* Arrest within 24 hours of admission.
* Immune deficiency or administration of immune suppressant drugs.
* Serum calcium greater than or equal to 10 mg/dl or phosphate greater than or equal 6 mg/dl.
* History of primary parathyroid disease.
* Metabolic bone disease.
* Sarcoidosis.
* End stage renal disease.
* receiving intermittent renal replacement therapy (RRT).
* Failure of enteral feeding or any contraindication to enteral administration.
* Obesity , body mass index (BMI \> 35 kg/m2)
* Known contraindication to vitamin C or thiamine (oxalate nephropathy or known glucose-6-phosphate dehydrogenase deficiency)
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
65 Years
Study:
NCT04216459
Study Brief:
Protocol Section:
NCT04216459