Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 3:14 AM
Ignite Modification Date:
2025-12-25 @ 3:14 AM
NCT ID:
NCT07199205
Eligibility Criteria:
Inclusion criteria:
* Adults aged 18 years and older.
* Diagnosed with prediabetes, defined according to the American Diabetes - - - - Association (ADA) criteria (fasting plasma glucose 100-125 mg/dL, HbA1c 5.7-6.4%, or 2-hour plasma glucose 140-199 mg/dL after oral glucose tolerance test).
* Baseline estimated glomerular filtration rate (eGFR) ≥60 mL/min/1.73 m² (CKD stages 1-2).
* Willingness to provide informed consent and comply with study procedures.
Exclusion criteria:
* Diagnosis of diabetes mellitus (fasting plasma glucose ≥126 mg/dL, HbA1c ≥6.5%).
* Established CKD stage 3 or higher (eGFR \<60 mL/min/1.73 m²).
* History of gout or current use of uric acid-lowering therapy (e.g., allopurinol, febuxostat) or acute gout.
* Use of medications known to significantly affect uric acid levels (e.g., thiazide diuretics, high-dose aspirin).
* Pregnancy or lactation.
* Presence of severe comorbid conditions (e.g., malignancy, active infection, advanced liver disease).
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT07199205
Study Brief:
Protocol Section:
NCT07199205