Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 3:10 AM
Ignite Modification Date:
2025-12-25 @ 3:10 AM
NCT ID:
NCT02304705
Eligibility Criteria:
Inclusion Criteria:
* Known chronic heart failure appropriately treated with Angiotensin converting enzyme (ACE) inhibitors and beta blockers, unless contraindicated or poorly tolerated
* indication for right heart catheterization
* pulmonary artery mean pressure \>25 mmHg
* pulmonary capillary wedge pressure \> 15 mmHg
* pulmonary vascular resistance \> 3 Wood units
Exclusion Criteria:
* hypersensitivity, allergy, or intolerable side effect to sildenafil
* history of primary pulmonary hypertension, connective tissue disorder, severe chronic obstructive pulmonary disorder (COPD), pulmonary embolism, or left to right shunt
* co-morbidities, limited exercise intolerance:
* morbid obesity (BMI \>40)
* COPD with oxygen dependence
* severe peripheral vascular disease with intermittent claudication
* status post amputation of lower extremity at any level
* severe degenerative joint disease preventing normal walking
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT02304705
Study Brief:
Protocol Section:
NCT02304705