Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 3:04 AM
Ignite Modification Date:
2025-12-25 @ 3:04 AM
NCT ID:
NCT00296933
Eligibility Criteria:
Inclusion Criteria:
* Males and Females
* Age: 18-50
* Recurrent Major Depressive Disorder; current Major Depressive Episode with at least one prior episode
* HAM-D \>16
* Able to give written informed consent
* Agree to use a reliable means of birth control during the study, as determined by the investigator (females of child-bearing potential only)
Exclusion Criteria:
* History of head injury or loss of consciousness for longer than 30 minutes
* Presence of primary anxiety disorder, bipolar I or II disorder, or psychotic disorders
* Presence of anorexia nervosa or bulimia nervosa
* Presence or history of epilepsy or other seizure disorders
* Presence of significant Axis II disorder based on investigator judgment
* Presence of significant unstable medical condition
* Presence or past history of ADHD or significant learning disability
* ECTs (unilateral) within the past 12 months or bilateral ECT (ever)
* More than 2 failed adequate antidepressant treatments in the current episode
* Pregnant or breast-feeding females
* Have received treatment within the last 30 days with an investigational drug
* Prior non-response to either bupropion-XL or escitalopram
* Current treatment with Zyban (bupropion hydrochloride)
* Antidepressant treatment within the last week (within the last 3 weeks fluoxetine)
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
50 Years
Study:
NCT00296933
Study Brief:
Protocol Section:
NCT00296933