Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 3:01 AM
Ignite Modification Date:
2025-12-25 @ 3:01 AM
NCT ID:
NCT02170233
Eligibility Criteria:
Inclusion Criteria:
* All patients age greater than 18 years who meet criteria of sepsis. Septic shock will be defined as those patients with severe sepsis and persistent hypotension (\<90mmHg systolic blood pressure) despite a fluid challenge of at least 20cc/kg
* Patients will only be considered eligible for enrollment if the treating physician plans to give at least 1-liter of crystalloid after initial US is performed
* A number (approximately 50 patients) with no symptoms of sepsis will be enrolled to assess measurements in healthy patients. These patients will only have one ultrasound performed for each of the desired study measures.
Exclusion Criteria:
* Patients unable to provide consent such as non-English speaking patients or patient/health care proxy unable to give consent
* History of significant trauma
* Incarcerated patients
* Failure to complete fluid challenge
* Pericardial disease or heart transplant. Patients with left bundle branch block, pulmonary hypertension, known systolic dysfunction (Ejection Fraction \<40%), receiving vasopressors, known moderate or severe valvular dysfunction, and irregular heart rhythms will be enrolled but analyzed separately
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT02170233
Study Brief:
Protocol Section:
NCT02170233