Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 3:00 AM
Ignite Modification Date:
2025-12-25 @ 3:00 AM
NCT ID:
NCT03624933
Eligibility Criteria:
Inclusion Criteria:
* ages 18-55
* meet DSM-5 diagnostic criteria for cannabis use disorder (cannabis use \>1 g/day, CUDIT score \>12)
* meet DSM-5 diagnostic criteria for Major Depressive Disorder as determined using the SCID
* be an outpatient receiving a stable dose of antidepressant medication(s) for at least 1 month
* have a Hamilton Depression Rating Scale (HDRS-17) baseline total score greater than 14
* have a Full Scale IQ greater than 80 as determined by the WTAR
* be a non-treatment seeking cannabis user
* evidence of sufficient motivation and effort as measure by a Test of Memory Malingering (TOMM) score greater than 45
* urinary baseline THC-COOH levels greater than 150 ng/ml
Exclusion Criteria:
* meets criteria for abuse or dependence of alcohol or other illicit substances within the part 6 months (with the exception of cannabis, nicotine, or caffeine)
* positive urine screen for illicit substances other than cannabis, nicotine or caffeine
* current suicidal or homicidal ideation
* psychotic disorder diagnosis (e.g. schizoaffective disorder, major depression with psychotic features) as determined by the SCID
* head injury with loss of consciousness greater than 2 minutes or requiring hospitalization
* neurological or medical condition determined to effect cognition
* be treatment seeking for cannabis use
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
55 Years
Study:
NCT03624933
Study Brief:
Protocol Section:
NCT03624933