Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 3:00 AM
Ignite Modification Date:
2025-12-25 @ 3:00 AM
NCT ID:
NCT07232433
Eligibility Criteria:
Inclusion Criteria:
* Age ≥ 18 years.
* Malignancy confirmed by histopathology or multidisciplinary team (MDT) discussion.
For a solitary GGN: size between 6-30 mm. For multiple GGNs: each measuring 6-30 mm, with no more than 3 nodules deemed to require treatment upon MDT consensus.
* Patient is ineligible for or unwilling to undergo video-assisted thoracoscopic surgery (VATS).
* Patient is ineligible for or declines radiotherapy or stereotactic body radiotherapy (SBRT).
* Eastern Cooperative Oncology Group (ECOG) performance status of 0 or 1.
* The subject demonstrates good compliance and has voluntarily provided written informed consent to participate.
Exclusion Criteria:
* Presence of severe cardiac, pulmonary, hepatic, or renal dysfunction, rendering the patient ineligible for general anesthesia.
* Contraindication to either bronchoscopy or computed tomography (CT)-guided percutaneous puncture.
* High risk associated with percutaneous puncture for at least one target lesion, or absence of a feasible access route as determined by pre-procedural bronchoscopic path planning.
* Platelet count \< 50 × 10⁹/L, or presence of an uncorrectable bleeding diathesis or coagulation disorder (prothrombin time \> 18 seconds, or prothrombin activity \< 40%).
* Concurrent participation in another interventional clinical trial, or anticipation of requiring additional antitumor therapy outside the scope of this study during the trial period.
* Any other condition deemed by the investigator to render the patient unsuitable for study participation.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT07232433
Study Brief:
Protocol Section:
NCT07232433